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DeCS
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Descriptor English:
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ADAM17 Protein
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Descriptor Spanish:
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Proteína ADAM17
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Descriptor Portuguese:
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Proteína ADAM17
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Synonyms English:
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ADAM 17 Protein
ADAM-17
ADAM-17 Protein
Antigen, CD156b
CD156b Antigen
Convertase, TNF-alpha
Disintegrin and Metalloproteinase Domain Containing Protein 17
Disintegrin and Metalloproteinase Domain-Containing Protein 17
TACA (Enzyme)
TACE (Enzyme)
TNF alpha Convertase
TNF alpha Converting Enzyme
TNF-alpha Convertase
TNF-alpha Converting Enzyme
Tumor Necrosis Factor Alpha Convertase
Tumor Necrosis Factor alpha Converting Enzyme
Tumor Necrosis Factor-alpha Convertase
Tumor Necrosis Factor-alpha Converting Enzyme
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Tree Number:
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D08.811.277.656.675.374.102.375
D09.400.430.500.375
D12.776.395.033.375
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Definition English:
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A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature form. It cleaves several other CELL SURFACE PROTEINS, including INTERLEUKIN-1 RECEPTOR TYPE II; TRANSFORMING GROWTH FACTOR ALPHA; L-SELECTIN; MUCIN-1; and AMYLOID BETA-PROTEIN PRECURSOR. It can also function as an activator of the Notch signaling pathway by mediating the cleavage of NOTCH RECEPTORS. |
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History Note English:
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2017 (1996)
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Allowable Qualifiers English:
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Record Number:
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56484
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Unique Identifier:
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D000072198
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Occurrence in VHL:
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Similar:
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DeCS
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